8th St.-Petersburg Brain Awareness Week
“The Power of Genes”
March 15th, 19:00 (GMT+3)
Talk title: Genetic drivers of tau pathology: causes, consequences and therapeutic opportunities
Summary of talk:
Most neurodegenerative diseases are caused by the accumulation of toxic proteins but each disease differs in which protein accumulates and which brain region is damaged. This presentation will use the example of tau protein accumulation in a pathology known as tauopathy that occurs in Alzheimer’s Disease (AD) and Frontotemporal lobe Dementia (FTD-tau) to illustrate some basic concepts of how genetics can cause the disease and determine the clinical phenotype, and what genes we might target to treat them.